Cargando…

Centromere protein U expression promotes non-small-cell lung cancer cell proliferation through FOXM1 and predicts poor survival

PURPOSE: Centromere protein U (CENPU) abnormally exhibits high expression in various types of human tumor tissues and participates in tumor progression; however, its expression pattern and biological function in lung cancer have not yet been elucidated. In the present study, we explored the clinical...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Xinxin, Chen, Diangang, Gao, Jianbao, Long, Haixia, Zha, Haoran, Zhang, Anmei, Shu, Chi, Zhou, Li, Yang, Fei, Zhu, Bo, Wu, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298391/ https://www.ncbi.nlm.nih.gov/pubmed/30588102 http://dx.doi.org/10.2147/CMAR.S182852

Ejemplares similares

C3a-C3aR signaling promotes breast cancer lung metastasis via modulating carcinoma associated fibroblasts
por: Shu, Chi, et al.
Publicado: (2020)

Overexpression of FOXM1 predicts poor prognosis and promotes cancer cell proliferation, migration and invasion in epithelial ovarian cancer
por: Wen, Ning, et al.
Publicado: (2014)

FoxM1 Promotes Cell Proliferation, Invasion, and Stem Cell Properties in Nasopharyngeal Carcinoma
por: Luo, Weiren, et al.
Publicado: (2018)

FoxM1 is Upregulated in Osteosarcoma and Inhibition of FoxM1 Decreases Osteosarcoma Cell Proliferation, Migration, and Invasion
por: Zhu, Xia, et al.
Publicado: (2020)

FoxM1 overexpression promotes cell proliferation and migration and inhibits apoptosis in hypopharyngeal squamous cell carcinoma resulting in poor clinical prognosis
por: Chen, Yan, et al.
Publicado: (2017)

FOXM1 and CENPF are associated with a poor prognosis through promoting proliferation and migration in lung adenocarcinoma
por: Li, Peipei, et al.
Publicado: (2023)

Circ-FOXM1 promotes the proliferation, migration and EMT process of osteosarcoma cells through FOXM1-mediated Wnt pathway activation
por: Zhang, Hao, et al.
Publicado: (2022)

MELK-Dependent FOXM1 Phosphorylation is Essential for Proliferation of Glioma Stem Cells
por: Joshi, Kaushal, et al.
Publicado: (2013)

FOXM1 regulates proliferation, senescence and oxidative stress in keratinocytes and cancer cells
por: Smirnov, Artem, et al.
Publicado: (2016)

FOXM1c is the predominant FOXM1 isoform expressed in cholangiocarcinoma that associated with metastatic potential and poor prognosis of patients
por: Klinhom-on, Nathakan, et al.
Publicado: (2021)

Centromere Protein I (CENP-I) Is Upregulated in Gastric Cancer, Predicts Poor Prognosis, and Promotes Tumor Cell Proliferation and Migration
por: Wang, Jiahui, et al.
Publicado: (2021)

Centromeric transcription maintains centromeric cohesion in human cells
por: Chen, Yujue, et al.
Publicado: (2021)

Overexpression of centromere protein K (CENPK) in ovarian cancer is correlated with poor patient survival and associated with predictive and prognostic relevance
por: Lee, Yi-Chao, et al.
Publicado: (2015)

Novel Nuclear Partnering Role of EPS8 With FOXM1 in Regulating Cell Proliferation
por: Ngan, Adaline Wan Ling, et al.
Publicado: (2019)

Tanshinone IIA suppresses gastric cancer cell proliferation and migration by downregulation of FOXM1
por: Yu, Jiao, et al.
Publicado: (2017)

Cell cycle and centromere FISH studies in premature centromere division
por: Corona-Rivera, Alfredo, et al.
Publicado: (2005)

Centromere protein U (CENPU) promotes gastric cancer cell proliferation and glycolysis by regulating high mobility group box 2 (HMGB2)
por: Deng, Taozhi, et al.
Publicado: (2021)

Overexpression of FoxM1 predicts poor prognosis of intrahepatic cholangiocarcinoma
por: Liu, Lingyun, et al.
Publicado: (2018)

FOXM1 regulates leukemia stem cell quiescence and survival in MLL-rearranged AML
por: Sheng, Yue, et al.
Publicado: (2020)

Constitutive centromere-associated network controls centromere drift in vertebrate cells
por: Hori, Tetsuya, et al.
Publicado: (2017)

Upregulation of FOXM1 in a subset of relapsed myeloma results in poor outcome
por: Gu, Chunyan, et al.
Publicado: (2018)

Circular PVT1 regulates cell proliferation and invasion via miR-149-5p/FOXM1 axis in ovarian cancer
por: Li, Min, et al.
Publicado: (2021)

Abnormal Expression of Centromere Protein U Is Associated with Hepatocellular Cancer Progression
por: Yu, Yuanlin, et al.
Publicado: (2021)

Proliferation-dependent positioning of individual centromeres in the interphase nucleus of human lymphoblastoid cell lines
por: Ollion, Jean, et al.
Publicado: (2015)

CENPE promotes lung adenocarcinoma proliferation and is directly regulated by FOXM1
por: Shan, Lina, et al.
Publicado: (2019)

β-Cell Proliferation, but Not Neogenesis, Following 60% Partial Pancreatectomy Is Impaired in the Absence of FoxM1
por: Ackermann Misfeldt, Amanda, et al.
Publicado: (2008)

Twist1 Promotes Gastric Cancer Cell Proliferation through Up-Regulation of FoxM1
por: Qian, Jianxin, et al.
Publicado: (2013)

Neuronal signals regulate obesity induced β-cell proliferation by FoxM1 dependent mechanism
por: Yamamoto, Junpei, et al.
Publicado: (2017)

Inactivation of the Akt/FOXM1 Signaling Pathway by Panobinostat Suppresses the Proliferation and Metastasis of Gastric Cancer Cells
por: Lee, Na-Ri, et al.
Publicado: (2021)

Downregulation of lncRNA PVT1 inhibits proliferation and migration of mesothelioma cells by targeting FOXM1
por: Fujii, Yutaro, et al.
Publicado: (2022)

Coordinated activation of c-Src and FOXM1 drives tumor cell proliferation and breast cancer progression
por: Nandi, Ipshita, et al.
Publicado: (2023)

The cell-penetrating FOXM1 N-terminus (M1-138) demonstrates potent inhibitory effects on cancer cells by targeting FOXM1 and FOXM1-interacting factor SMAD3
por: Zhang, Zhenwang, et al.
Publicado: (2019)

Caffeine Supplementation and FOXM1 Inhibition Enhance the Antitumor Effect of Statins in Neuroblastoma
por: Tran, Gia-Buu, et al.
Publicado: (2023)

FOXM1/lncRNA TYMSOS/miR-214-3p–Mediated High Expression of NCAPG Correlates With Poor Prognosis and Cell Proliferation in Non–Small Cell Lung Carcinoma
por: Yuan, Yixiao, et al.
Publicado: (2022)

Overexpression of Forkhead Box Protein M1 (FOXM1) in Ovarian Cancer Correlates with Poor Patient Survival and Contributes to Paclitaxel Resistance
por: Zhao, Fung, et al.
Publicado: (2014)

Expression of FSCN1 and FOXM1 are associated with poor prognosis of adrenocortical carcinoma patients
por: Liang, Jiayu, et al.
Publicado: (2019)

FOXM1: Functional Roles of FOXM1 in Non-Malignant Diseases
por: Zhang, Zhenwang, et al.
Publicado: (2023)

Centromere Protein N Participates in Cellular Proliferation of Human Oral Cancer by Cell-Cycle Enhancement
por: Oka, Noritoshi, et al.
Publicado: (2019)

A human B-cell interactome identifies MYB and FOXM1 as master regulators of proliferation in germinal centers
por: Lefebvre, Celine, et al.
Publicado: (2010)

The critical role of dysregulated Hh-FOXM1-TPX2 signaling in human hepatocellular carcinoma cell proliferation
por: Wang, Yiting, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_6c1bbho35avp1jsnlmfgs8m1p6