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A Novel Approach of Identifying Immunodominant Self and Viral Antigen Cross-Reactive T Cells and Defining the Epitopes They Recognize

Infection and vaccination can lead to activation of autoreactive T cells, including the activation of cross-reactive T cells. However, detecting these cross-reactive T cells and identifying the non-self and self-antigen epitopes is difficult. The current study demonstrates the utility of a novel app...

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Detalles Bibliográficos
Autores principales: Yang, Junbao, Jing, Lichen, James, Eddie A., Gebe, John A., Koelle, David M., Kwok, William W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298415/
https://www.ncbi.nlm.nih.gov/pubmed/30619245
http://dx.doi.org/10.3389/fimmu.2018.02811