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Unraveling the structural basis for the exceptional stability of RNA G-quadruplexes capped by a uridine tetrad at the 3′ terminus

Uridine tetrads (U-tetrads) are a structural element encountered in RNA G-quadruplexes, for example, in the structures formed by the biologically relevant human telomeric repeat RNA. For these molecules, an unexpectedly strong stabilizing influence of a U-tetrad forming at the 3′ terminus of a quadr...

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Detalles Bibliográficos
Autores principales: Andrałojć, Witold, Małgowska, Magdalena, Sarzyńska, Joanna, Pasternak, Karol, Szpotkowski, Kamil, Kierzek, Ryszard, Gdaniec, Zofia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298561/
https://www.ncbi.nlm.nih.gov/pubmed/30341177
http://dx.doi.org/10.1261/rna.068163.118

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