Apobec1 complementation factor (A1CF) and RBM47 interact in tissue-specific regulation of C to U RNA editing in mouse intestine and liver

Mammalian C to U RNA is mediated by APOBEC1, the catalytic deaminase, together with RNA binding cofactors (including A1CF and RBM47) whose relative physiological requirements are unresolved. Although A1CF complements APOBEC1 for in vitro RNA editing, A1cf(–/–) mice exhibited no change in apolipoprot...

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Detalles Bibliográficos
Autores principales: Blanc, Valerie, Xie, Yan, Kennedy, Susan, Riordan, Jesse D., Rubin, Deborah C., Madison, Blair B., Mills, Jason C., Nadeau, Joseph H., Davidson, Nicholas O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298562/
https://www.ncbi.nlm.nih.gov/pubmed/30309881
http://dx.doi.org/10.1261/rna.068395.118

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