Cargando…
Single-cell copy number variant detection reveals the dynamics and diversity of adaptation
Copy number variants (CNVs) are a pervasive source of genetic variation and evolutionary potential, but the dynamics and diversity of CNVs within evolving populations remain unclear. Long-term evolution experiments in chemostats provide an ideal system for studying the molecular processes underlying...
Autores principales: | Lauer, Stephanie, Avecilla, Grace, Spealman, Pieter, Sethia, Gunjan, Brandt, Nathan, Levy, Sasha F., Gresham, David |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298651/ https://www.ncbi.nlm.nih.gov/pubmed/30562346 http://dx.doi.org/10.1371/journal.pbio.3000069 |
Ejemplares similares
-
Copy number variation alters local and global mutational tolerance
por: Avecilla, Grace, et al.
Publicado: (2023) -
Post-transcriptional mechanisms modulate the consequences of adaptive copy number variation
por: Spealman, Pieter, et al.
Publicado: (2023) -
Complex Genomic Rearrangements following Selection in a Glutamine-Limited Medium over Hundreds of Generations
por: Spealman, Pieter, et al.
Publicado: (2022) -
Best Practices in Microbial Experimental Evolution: Using Reporters and Long-Read Sequencing to Identify Copy Number Variation in Experimental Evolution
por: Spealman, Pieter, et al.
Publicado: (2023) -
Inverted duplicate DNA sequences increase translocation rates through sequencing nanopores resulting in reduced base calling accuracy
por: Spealman, Pieter, et al.
Publicado: (2020)