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TLR4 deficiency reduces pulmonary resistance to Streptococcus pneumoniae in gut microbiota-disrupted mice

Streptococcus pneumoniae is a clinically important pathogen responsible for significant morbidity and mortality worldwide. Disruption of the host gut microbiota by antibiotics reduces the pulmonary resistance to S. pneumoniae. The aim of our study was to determine the potential role of TLR4 in the r...

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Detalles Bibliográficos
Autores principales:	Wang, Hongyan, Lian, Pengjing, Niu, Xiaofei, Zhao, Lihong, Mu, Xiang, Feng, Bo, Li, Jingyun, Liang, Zhenni, Qiao, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298678/ https://www.ncbi.nlm.nih.gov/pubmed/30562386 http://dx.doi.org/10.1371/journal.pone.0209183

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