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Immunogenic particles with a broad antigenic spectrum stimulate cytolytic T cells and offer increased protection against EBV infection ex vivo and in mice
The ubiquitous Epstein-Barr virus (EBV) is the primary cause of infectious mononucleosis and is etiologically linked to the development of several malignancies and autoimmune diseases. EBV has a multifaceted life cycle that comprises virus lytic replication and latency programs. Considering EBV infe...
Autores principales: | van Zyl, Dwain G., Tsai, Ming-Han, Shumilov, Anatoliy, Schneidt, Viktor, Poirey, Rémy, Schlehe, Bettina, Fluhr, Herbert, Mautner, Josef, Delecluse, Henri-Jacques |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298685/ https://www.ncbi.nlm.nih.gov/pubmed/30521644 http://dx.doi.org/10.1371/journal.ppat.1007464 |
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