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“TRPV1 is a component of the atrial natriuretic signaling complex, and using orally delivered antagonists, presents a valid therapeutic target in the longitudinal reversal and treatment of cardiac hypertrophy and heart failure”
Activation of the atrial natriuretic signaling pathway is intrinsic to the pathological responses associated with a range of cardiovascular diseases that stress the heart, especially those involved in sustained cardiac pressure overload which induces hypertrophy and the pathological remodeling that...
Autores principales: | Horton, Jaime S., Shiraishi, Takuya, Alfulaij, Naghum, Small-Howard, Andrea L., Turner, Helen C., Kurokawa, Tatsuki, Mori, Yasuo, Stokes, Alexander J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298697/ https://www.ncbi.nlm.nih.gov/pubmed/30424709 http://dx.doi.org/10.1080/19336950.2018.1547611 |
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