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Functional and structural similarity of human DNA primase [4Fe4S] cluster domain constructs

The regulatory subunit of human DNA primase has a C-terminal domain (p58C) that contains a [4Fe4S] cluster and binds DNA. Previous electrochemical analysis of a p58C construct revealed that its affinity for DNA is sensitive to the redox state of the [4Fe4S] cluster. Concerns about the validity of th...

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Detalles Bibliográficos
Autores principales:	Holt, Marilyn E., Salay, Lauren E., O’Brien, Elizabeth, Barton, Jacqueline K., Chazin, Walter J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298731/ https://www.ncbi.nlm.nih.gov/pubmed/30562384 http://dx.doi.org/10.1371/journal.pone.0209345

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