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Privatisation rescues function following loss of cooperation

A single cheating mutant can lead to the invasion and eventual eradication of cooperation from a population. Consequently, cheat invasion is often considered equal to extinction in empirical and theoretical studies of cooperator-cheat dynamics. But does cheat invasion necessarily equate extinction i...

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Autores principales: Andersen, Sandra Breum, Ghoul, Melanie, Marvig, Rasmus L, Lee, Zhuo-Bin, Molin, Søren, Johansen, Helle Krogh, Griffin, Ashleigh S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298776/
https://www.ncbi.nlm.nih.gov/pubmed/30558711
http://dx.doi.org/10.7554/eLife.38594
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author Andersen, Sandra Breum
Ghoul, Melanie
Marvig, Rasmus L
Lee, Zhuo-Bin
Molin, Søren
Johansen, Helle Krogh
Griffin, Ashleigh S
author_facet Andersen, Sandra Breum
Ghoul, Melanie
Marvig, Rasmus L
Lee, Zhuo-Bin
Molin, Søren
Johansen, Helle Krogh
Griffin, Ashleigh S
author_sort Andersen, Sandra Breum
collection PubMed
description A single cheating mutant can lead to the invasion and eventual eradication of cooperation from a population. Consequently, cheat invasion is often considered equal to extinction in empirical and theoretical studies of cooperator-cheat dynamics. But does cheat invasion necessarily equate extinction in nature? By following the social dynamics of iron metabolism in Pseudomonas aeruginosa during cystic fibrosis lung infection, we observed that individuals evolved to replace cooperation with a ‘private’ behaviour. Phenotypic assays showed that cooperative iron acquisition frequently was upregulated early in infection, which, however, increased the risk of cheat invasion. With whole-genome sequencing we showed that if, and only if, cooperative iron acquisition is lost from the population, a private system was upregulated. The benefit of upregulation depended on iron availability. These findings highlight the importance of social dynamics of natural populations and emphasizes the potential impact of past social interaction on the evolution of private traits.
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spelling pubmed-62987762018-12-18 Privatisation rescues function following loss of cooperation Andersen, Sandra Breum Ghoul, Melanie Marvig, Rasmus L Lee, Zhuo-Bin Molin, Søren Johansen, Helle Krogh Griffin, Ashleigh S eLife Evolutionary Biology A single cheating mutant can lead to the invasion and eventual eradication of cooperation from a population. Consequently, cheat invasion is often considered equal to extinction in empirical and theoretical studies of cooperator-cheat dynamics. But does cheat invasion necessarily equate extinction in nature? By following the social dynamics of iron metabolism in Pseudomonas aeruginosa during cystic fibrosis lung infection, we observed that individuals evolved to replace cooperation with a ‘private’ behaviour. Phenotypic assays showed that cooperative iron acquisition frequently was upregulated early in infection, which, however, increased the risk of cheat invasion. With whole-genome sequencing we showed that if, and only if, cooperative iron acquisition is lost from the population, a private system was upregulated. The benefit of upregulation depended on iron availability. These findings highlight the importance of social dynamics of natural populations and emphasizes the potential impact of past social interaction on the evolution of private traits. eLife Sciences Publications, Ltd 2018-12-18 /pmc/articles/PMC6298776/ /pubmed/30558711 http://dx.doi.org/10.7554/eLife.38594 Text en © 2018, Andersen et al http://creativecommons.org/licenses/by/4.0/ http://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use and redistribution provided that the original author and source are credited.
spellingShingle Evolutionary Biology
Andersen, Sandra Breum
Ghoul, Melanie
Marvig, Rasmus L
Lee, Zhuo-Bin
Molin, Søren
Johansen, Helle Krogh
Griffin, Ashleigh S
Privatisation rescues function following loss of cooperation
title Privatisation rescues function following loss of cooperation
title_full Privatisation rescues function following loss of cooperation
title_fullStr Privatisation rescues function following loss of cooperation
title_full_unstemmed Privatisation rescues function following loss of cooperation
title_short Privatisation rescues function following loss of cooperation
title_sort privatisation rescues function following loss of cooperation
topic Evolutionary Biology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298776/
https://www.ncbi.nlm.nih.gov/pubmed/30558711
http://dx.doi.org/10.7554/eLife.38594
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