Highly efficient 5' capping of mitochondrial RNA with NAD(+) and NADH by yeast and human mitochondrial RNA polymerase

Bacterial and eukaryotic nuclear RNA polymerases (RNAPs) cap RNA with the oxidized and reduced forms of the metabolic effector nicotinamide adenine dinucleotide, NAD(+) and NADH, using NAD(+) and NADH as non-canonical initiating nucleotides for transcription initiation. Here, we show that mitochondr...

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Detalles Bibliográficos
Autores principales: Bird, Jeremy G, Basu, Urmimala, Kuster, David, Ramachandran, Aparna, Grudzien-Nogalska, Ewa, Towheed, Atif, Wallace, Douglas C, Kiledjian, Megerditch, Temiakov, Dmitry, Patel, Smita S, Ebright, Richard H, Nickels, Bryce E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298784/
https://www.ncbi.nlm.nih.gov/pubmed/30526856
http://dx.doi.org/10.7554/eLife.42179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298784/
https://www.ncbi.nlm.nih.gov/pubmed/30526856
http://dx.doi.org/10.7554/eLife.42179

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