A Chymase Inhibitory RNA Aptamer Improves Cardiac Function and Survival after Myocardial Infarction

We have reported that mast cell chymase, an angiotensin II-generating enzyme, is important in cardiovascular tissues. Recently, we developed a new chymase-specific inhibitory RNA aptamer, HA28, and we evaluated the effects of HA28 on cardiac function and the mortality rate after myocardial infarctio...

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Detalles Bibliográficos
Autores principales: Jin, Denan, Takai, Shinji, Nonaka, Yosuke, Yamazaki, Satoko, Fujiwara, Masatoshi, Nakamura, Yoshikazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298900/
https://www.ncbi.nlm.nih.gov/pubmed/30572223
http://dx.doi.org/10.1016/j.omtn.2018.11.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298900/
https://www.ncbi.nlm.nih.gov/pubmed/30572223
http://dx.doi.org/10.1016/j.omtn.2018.11.001

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