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HAI Peptide and Backbone Analogs—Validation and Enhancement of Biostability and Bioactivity of BBB Shuttles

Low effectiveness and resistance to treatments are commonplace in disorders of the central nervous system (CNS). These issues concern mainly the blood-brain barrier (BBB), which preserves homeostasis in the brain and protects this organ from toxic molecules and biohazards by regulating transport thr...

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Detalles Bibliográficos
Autores principales: Arranz-Gibert, Pol, Prades, Roger, Guixer, Bernat, Guerrero, Simón, Araya, Eyleen, Ciudad, Sonia, Kogan, Marcelo J., Giralt, Ernest, Teixidó, Meritxell
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298966/
https://www.ncbi.nlm.nih.gov/pubmed/30560894
http://dx.doi.org/10.1038/s41598-018-35938-8