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HAI Peptide and Backbone Analogs—Validation and Enhancement of Biostability and Bioactivity of BBB Shuttles
Low effectiveness and resistance to treatments are commonplace in disorders of the central nervous system (CNS). These issues concern mainly the blood-brain barrier (BBB), which preserves homeostasis in the brain and protects this organ from toxic molecules and biohazards by regulating transport thr...
Autores principales: | Arranz-Gibert, Pol, Prades, Roger, Guixer, Bernat, Guerrero, Simón, Araya, Eyleen, Ciudad, Sonia, Kogan, Marcelo J., Giralt, Ernest, Teixidó, Meritxell |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298966/ https://www.ncbi.nlm.nih.gov/pubmed/30560894 http://dx.doi.org/10.1038/s41598-018-35938-8 |
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