High-resolution deconstruction of evolution induced by chemotherapy treatments in breast cancer xenografts

The processes by which tumors evolve are essential to the efficacy of treatment, but quantitative understanding of intratumoral dynamics has been limited. Although intratumoral heterogeneity is common, quantification of evolution is difficult from clinical samples because treatment replicates cannot...

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Detalles Bibliográficos
Autores principales: Kim, Hyunsoo, Kumar, Pooja, Menghi, Francesca, Noorbakhsh, Javad, Cerveira, Eliza, Ryan, Mallory, Zhu, Qihui, Ananda, Guruprasad, George, Joshy, Chen, Henry C., Mockus, Susan, Zhang, Chengsheng, Yang, Yan, Keck, James, Karuturi, R. Krishna Murthy, Bult, Carol J., Lee, Charles, Liu, Edison T., Chuang, Jeffrey H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298990/
https://www.ncbi.nlm.nih.gov/pubmed/30560892
http://dx.doi.org/10.1038/s41598-018-36184-8

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