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The Dopamine Allosteric Agent, PAOPA, Demonstrates Therapeutic Potential in the Phencyclidine NMDA Pre-clinical Rat Model of Schizophrenia

PAOPA, a potent analog of prolyl-leucyl-glycinamide, has shown therapeutic potential at the preclinical stage for dopaminergic related illnesses, including animal models of schizophrenia, Parkinson’s disease and haloperidol-induced extrapyramidal movement disorders. PAOPA’s unique allosteric mechani...

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Detalles Bibliográficos
Autores principales:	Daya, Ritesh P., Bhandari, Jayant, Kooner, Sharnpreet K., Ho, Joella, Rowley, Christopher D., Bock, Nicholas A., Farncombe, Troy, Mishra, Ram K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299008/ https://www.ncbi.nlm.nih.gov/pubmed/30618660 http://dx.doi.org/10.3389/fnbeh.2018.00302

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