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Hyperforin Potentiates Antidepressant-Like Activity of Lanicemine in Mice
N-methyl-D-aspartate receptor (NMDAR) modulators induce rapid and sustained antidepressant like-activity in rodents through a molecular mechanism of action that involves the activation of Ca(2+) dependent signaling pathways. Moreover, ketamine, a global NMDAR antagonist is a potent, novel, and atypi...
Autores principales: | Pochwat, Bartłomiej, Szewczyk, Bernadeta, Kotarska, Katarzyna, Rafało-Ulińska, Anna, Siwiec, Marcin, Sowa, Joanna E., Tokarski, Krzysztof, Siwek, Agata, Bouron, Alexandre, Friedland, Kristina, Nowak, Gabriel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299069/ https://www.ncbi.nlm.nih.gov/pubmed/30618608 http://dx.doi.org/10.3389/fnmol.2018.00456 |
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