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Defective Autophagy in T Cells Impairs the Development of Diet-Induced Hepatic Steatosis and Atherosclerosis
Macroautophagy (or autophagy) is a conserved cellular process in which cytoplasmic cargo is targeted for lysosomal degradation. Autophagy is crucial for the functional integrity of different subsets of T cells in various developmental stages. Since atherosclerosis is an inflammatory disease of the v...
Autores principales: | Amersfoort, Jacob, Douna, Hidde, Schaftenaar, Frank H., Foks, Amanda C., Kröner, Mara J., van Santbrink, Peter J., van Puijvelde, Gijs H. M., Bot, Ilze, Kuiper, Johan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299070/ https://www.ncbi.nlm.nih.gov/pubmed/30619297 http://dx.doi.org/10.3389/fimmu.2018.02937 |
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