miR-100 maintains phenotype of tumor-associated macrophages by targeting mTOR to promote tumor metastasis via Stat5a/IL-1ra pathway in mouse breast cancer

Tumor-associated macrophages (TAMs), the main part of immune cells in tumor microenvironment (TME), play a potent role in promoting tumorigenesis through mechanisms such as stimulating angiogenesis, enhancing tumor migration and suppressing antitumor immunity. MicroRNAs (miRNAs) are considered as cr...

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Detalles Bibliográficos
Autores principales: Wang, Wei, Liu, Yan, Guo, Jian, He, Huiwen, Mi, Xue, Chen, Chong, Xie, Junling, Wang, Shengnan, Wu, Peng, Cao, Fengqi, Bai, Lipeng, Si, Qin, Xiang, Rong, Luo, Yunping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299090/
https://www.ncbi.nlm.nih.gov/pubmed/30563983
http://dx.doi.org/10.1038/s41389-018-0106-y

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