Atypical GATA transcription factor TRPS1 represses gene expression by recruiting CHD4/NuRD(MTA2) and suppresses cell migration and invasion by repressing TP63 expression

Transcriptional repressor GATA binding 1 (TRPS1), an atypical GATA transcription factor, functions as a transcriptional repressor and is also implicated in human cancers. However, the underlying mechanism of TRPS1 contributing to malignancy remains obscure. In the current study, we report that TRPS1...

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Detalles Bibliográficos
Autores principales: Wang, Yuzhi, Lin, Xue, Gong, Xue, Wu, Lele, Zhang, Jun, Liu, Weiguang, Li, Jian, Chen, Liming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299095/
https://www.ncbi.nlm.nih.gov/pubmed/30563971
http://dx.doi.org/10.1038/s41389-018-0108-9

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