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Hidden heterogeneity and circadian-controlled cell fate inferred from single cell lineages

The origin of lineage correlations among single cells and the extent of heterogeneity in their intermitotic times (IMT) and apoptosis times (AT) remain incompletely understood. Here we developed single cell lineage-tracking experiments and computational algorithms to uncover correlations and heterog...

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Detalles Bibliográficos
Autores principales: Chakrabarti, Shaon, Paek, Andrew L., Reyes, Jose, Lasick, Kathleen A., Lahav, Galit, Michor, Franziska
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299096/
https://www.ncbi.nlm.nih.gov/pubmed/30560953
http://dx.doi.org/10.1038/s41467-018-07788-5