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Drug discovery of anticancer drugs targeting methylenetetrahydrofolate dehydrogenase 2

Many anticancer drugs have serious adverse effects; therefore, it is necessary to target features specific to cancer cells to minimize the effects on healthy cells. Methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) was reported to be specifically enhanced in cancer. We confirmed the validity of MTH...

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Detalles Bibliográficos
Autores principales:	Asai, Ayumu, Koseki, Jun, Konno, Masamitsu, Nishimura, Tatsunori, Gotoh, Noriko, Satoh, Taroh, Doki, Yuichiro, Mori, Masaki, Ishii, Hideshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299143/ https://www.ncbi.nlm.nih.gov/pubmed/30582043 http://dx.doi.org/10.1016/j.heliyon.2018.e01021

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