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Estimating the concentration of therapeutic range using disease-specific iPS cells: Low-dose rapamycin therapy for Pendred syndrome
INTRODUCTION: Pendred syndrome is an autosomal-recessive disease characterized by congenital hearing loss and thyroid goiter. Previously, cell stress susceptibilities were shown to increase in patient-derived cells with intracellular aggregation using an in vitro acute cochlear cell model derived fr...
Autores principales: | Hosoya, Makoto, Saeki, Tsubasa, Saegusa, Chika, Matsunaga, Tatsuo, Okano, Hideyuki, Fujioka, Masato, Ogawa, Kaoru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Japanese Society for Regenerative Medicine
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299162/ https://www.ncbi.nlm.nih.gov/pubmed/30581897 http://dx.doi.org/10.1016/j.reth.2018.11.001 |
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