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CpaA Is a Glycan-Specific Adamalysin-like Protease Secreted by Acinetobacter baumannii That Inactivates Coagulation Factor XII
Antibiotic-resistant Acinetobacter baumannii is increasingly recognized as a cause of difficult-to-treat nosocomial infections, including pneumonia, wound infections, and bacteremia. Previous studies have demonstrated that the metalloprotease CpaA contributes to virulence and prolongs clotting time...
Autores principales: | Waack, Ursula, Warnock, Mark, Yee, Andrew, Huttinger, Zachary, Smith, Sara, Kumar, Ayush, Deroux, Alban, Ginsburg, David, Mobley, Harry L. T., Lawrence, Daniel A., Sandkvist, Maria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299215/ https://www.ncbi.nlm.nih.gov/pubmed/30563903 http://dx.doi.org/10.1128/mBio.01606-18 |
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