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Structure, activation and dysregulation of fibroblast growth factor receptor kinases: perspectives for clinical targeting

The receptor tyrosine kinase family of fibroblast growth factor receptors (FGFRs) play crucial roles in embryonic development, metabolism, tissue homeostasis and wound repair via stimulation of intracellular signalling cascades. As a consequence of FGFRs’ influence on cell growth, proliferation and...

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Detalles Bibliográficos
Autores principales:	Farrell, Brendan, Breeze, Alexander L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2018
Materias:	Review Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299260/ https://www.ncbi.nlm.nih.gov/pubmed/30545934 http://dx.doi.org/10.1042/BST20180004

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