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SRC-3 protects intestine from DSS-induced colitis by inhibiting inflammation and promoting goblet cell differentiation through enhancement of KLF4 expression

Goblet cell loss, which leads to the reduction of mucin secretion, is a hallmark of ulcerative colitis (UC). We previously reported that steroid receptor coactivator 3 (SRC-3), a transcriptional coactivator, contributes to host defense against Citrobacter rodentium by recruiting neutrophils, suggest...

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Detalles Bibliográficos
Autores principales:	Chen, Wenbo, Zhuo, Minghui, Lu, Xuqiang, Xia, Xiaochun, Zhao, Yang, Huang, Zhengrong, Xu, Jianming, Li, Weihua, Yu, Chundong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299374/ https://www.ncbi.nlm.nih.gov/pubmed/30585268 http://dx.doi.org/10.7150/ijbs.28576

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