Islet α-cell Inflammation Induced By NF-κB inducing kinase (NIK) Leads to Hypoglycemia, Pancreatitis, Growth Retardation, and Postnatal Death in Mice

Islet α-cell dysfunction has been shown to contribute to type 2 diabetes; however, whether islet α-cell inflammation is involved in the occurrence of pancreatitis is largely unknown. The aims of this study were to investigate how NF-κB inducing kinase (NIK) regulates pancreatic α-cell function, both...

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Detalles Bibliográficos
Autores principales: Li, Xinzhi, Jia, Linna, Chen, Xiaoyue, Dong, Ying, Ren, Xiaomeng, Dong, Yuefan, Chen, Ying, Xie, Liwei, Liu, Ming, Shiota, Chiyo, Gittes, George K., Rui, Liangyou, Chen, Zheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299425/
https://www.ncbi.nlm.nih.gov/pubmed/30613274
http://dx.doi.org/10.7150/thno.28960

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