Cargando…

T-cell functionality testing is highly relevant to developing novel immuno-tracers monitoring T cells in the context of immunotherapies and revealed CD7 as an attractive target

Cancer immunotherapy has proven high efficacy in treating diverse cancer entities by immune checkpoint modulation and adoptive T-cell transfer. However, patterns of treatment response differ substantially from conventional therapies, and reliable surrogate markers are missing for early detection of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mayer, Kristine E., Mall, Sabine, Yusufi, Nahid, Gosmann, Dario, Steiger, Katja, Russelli, Lisa, Bianchi, Henrique de Oliviera, Audehm, Stefan, Wagner, Ricarda, Bräunlein, Eva, Stelzl, Anja, Bassermann, Florian, Weichert, Wilko, Weber, Wolfgang, Schwaiger, Markus, D'Alessandria, Calogero, Krackhardt, Angela M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299443/ https://www.ncbi.nlm.nih.gov/pubmed/30613283 http://dx.doi.org/10.7150/thno.27275

Ejemplares similares

In-depth Characterization of a TCR-specific Tracer for Sensitive Detection of Tumor-directed Transgenic T Cells by Immuno-PET
por: Yusufi, Nahid, et al.
Publicado: (2017)

Promise and challenges of clinical non-invasive T-cell tracking in the era of cancer immunotherapy
por: Gosmann, Dario, et al.
Publicado: (2022)

A Semi Rigid Novel Hydroxamate AMPED-Based Ligand for (89)Zr PET Imaging
por: Russelli, Lisa, et al.
Publicado: (2021)

P70. Development of clinically implementable imaging strategies for tracking T cell receptor-transgenic T cells
por: Mall, S, et al.
Publicado: (2014)

Gene editing enables T-cell engineering to redirect antigen specificity for potent tumor rejection
por: Albers, Julian J, et al.
Publicado: (2019)

Functional analysis of peripheral and intratumoral neoantigen-specific TCRs identified in a patient with melanoma
por: Bräunlein, Eva, et al.
Publicado: (2021)

Key Features Relevant to Select Antigens and TCR From the MHC-Mismatched Repertoire to Treat Cancer
por: Audehm, Stefan, et al.
Publicado: (2019)

Preclinical biodistribution and dosimetry and human biodistribution comparing (18)F-rhPSMA-7 and single isomer (18)F-rhPSMA-7.3
por: Knorr, Karina, et al.
Publicado: (2022)

Galectin-3: The Impact on the Clinical Management of Patients with Thyroid Nodules and Future Perspectives
por: Bartolazzi, Armando, et al.
Publicado: (2018)

Identification and Characterization of Neoantigens As Well As Respective Immune Responses in Cancer Patients
por: Bräunlein, Eva, et al.
Publicado: (2017)

Correlation of in vivo imaging to morphomolecular pathology in translational research: challenge accepted
por: Ballke, Simone, et al.
Publicado: (2021)

Effective rational humanization of a PASylated anti-galectin-3 Fab for the sensitive PET imaging of thyroid cancer in vivo
por: Peplau, Emanuel, et al.
Publicado: (2021)

Is Hypoxia a Factor Influencing PSMA-Directed Radioligand Therapy?—An In Silico Study on the Role of Chronic Hypoxia in Prostate Cancer
por: Birindelli, Gabriele, et al.
Publicado: (2021)

Systematically evaluating DOTATATE and FDG as PET immuno-imaging tracers of cardiovascular inflammation
por: Toner, Yohana C., et al.
Publicado: (2022)

Hyperkalemia in patients treated with endoradiotherapy combined with amino acid infusion is associated with severe metabolic acidosis
por: Pfob, Christian H., et al.
Publicado: (2018)

Correction to: In vivo imaging of early stages of rheumatoid arthritis by α5β1-integrin-targeted positron emission tomography
por: Notni, Johannes, et al.
Publicado: (2019)

In vivo imaging of early stages of rheumatoid arthritis by α5β1-integrin-targeted positron emission tomography
por: Notni, Johannes, et al.
Publicado: (2019)

Evaluation of an ImmunoPET Tracer for IL-12 in a Preclinical Model of Inflammatory Immune Responses
por: Viola, Nerissa T., et al.
Publicado: (2022)

There is a world beyond αvβ3-integrin: Multimeric ligands for imaging of the integrin subtypes αvβ6, αvβ8, αvβ3, and α5β1 by positron emission tomography
por: Steiger, Katja, et al.
Publicado: (2021)

New pathogen-specific immunoPET/MR tracer for molecular imaging of a systemic bacterial infection
por: Wiehr, Stefan, et al.
Publicado: (2016)

Can we produce an image of bacteria with radiopharmaceuticals?
por: Signore, A., et al.
Publicado: (2008)

Effect of Carbohydration on the Theranostic Tracer PSMA I&T
por: Schmidt, Alexander, et al.
Publicado: (2018)

The other immuno-PET: Metabolic tracers in evaluation of immune responses to immune checkpoint inhibitor therapy for solid tumors
por: Levi, Jelena, et al.
Publicado: (2023)

CD137 as an Attractive T Cell Co-Stimulatory Target in the TNFRSF for Immuno-Oncology Drug Development
por: Hashimoto, Kenji
Publicado: (2021)

Genetically Engineered Mouse Models of Liver Tumorigenesis Reveal a Wide Histological Spectrum of Neoplastic and Non-Neoplastic Liver Lesions
por: Steiger, Katja, et al.
Publicado: (2020)

uPA‐PAI‐1 heteromerization promotes breast cancer progression by attracting tumorigenic neutrophils
por: Uhl, Bernd, et al.
Publicado: (2021)

Enhanced Safety and Efficacy of Oncolytic VSV Therapy by Combination with T Cell Receptor Transgenic T Cells as Carriers
por: Melzer, Michael Karl, et al.
Publicado: (2018)

Perspective of α(v)β(6)-Integrin Imaging for Clinical Management of Pancreatic Carcinoma and Its Precursor Lesions
por: Steiger, Katja, et al.
Publicado: (2017)

The limits of molecular signatures for pancreatic ductal adenocarcinoma subtyping
por: Lautizi, Manuela, et al.
Publicado: (2022)

Synthesis and Preclinical Evaluation of (177)Lu-Labeled Radiohybrid PSMA Ligands for Endoradiotherapy of Prostate Cancer
por: Wurzer, Alexander, et al.
Publicado: (2022)

Response assessment with the CXCR4-directed positron emission tomography tracer [(68)Ga]Pentixafor in a patient with extranodal marginal zone lymphoma of the orbital cavities
por: Herhaus, Peter, et al.
Publicado: (2017)

Synthesis and Optimization of the Labeling Procedure of (99m)Tc-Hynic-Interleukin-2 for In vivo Imaging of Activated T lymphocytes
por: D’Alessandria, Calogero, et al.
Publicado: (2009)

Direct identification of clinically relevant neoepitopes presented on native human melanoma tissue by mass spectrometry
por: Bassani-Sternberg, Michal, et al.
Publicado: (2016)

Tracking a TGF-β activator in vivo: sensitive PET imaging of αvβ8-integrin with the Ga-68-labeled cyclic RGD octapeptide trimer Ga-68-Triveoctin
por: Quigley, Neil Gerard, et al.
Publicado: (2020)

Circulating Tumor DNA Profiling of a Diffuse Large B Cell Lymphoma Patient with Secondary Acute Myeloid Leukemia
por: Kerle, Irina A., et al.
Publicado: (2022)

Synthesis and Preclinical Characterization of the PSMA-Targeted Hybrid Tracer PSMA-I&F for Nuclear and Fluorescence Imaging of Prostate Cancer
por: Schottelius, Margret, et al.
Publicado: (2019)

Proteogenomic analysis reveals RNA as a source for tumor-agnostic neoantigen identification
por: Tretter, Celina, et al.
Publicado: (2023)

Imaging atherosclerotic plaques by targeting Galectin-3 and activated macrophages using ((89)Zr)-DFO- Galectin3-F(ab')(2) mAb
por: Varasteh, Zohreh, et al.
Publicado: (2021)

Vascular Remodeling Is a Crucial Event in the Early Phase of Hepatocarcinogenesis in Rodent Models for Liver Tumorigenesis
por: Tulessin, Margaret, et al.
Publicado: (2022)

Risk stratification in luminal-type breast cancer: Comparison of Ki-67 with EndoPredict test results
por: Noske, Aurelia, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_8uqrd9ckiftqd9n6t77k0atbs4