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Delivery of miR-146a to Ly6C(high) Monocytes Inhibits Pathogenic Bone Erosion in Inflammatory Arthritis

Rationale: Monocytes play critical roles in the pathogenesis of arthritis by contributing to the inflammatory response and bone erosion. Among genes involved in regulating monocyte functions, miR-146a negatively regulates the inflammatory response and osteoclast differentiation of monocytes. It is a...

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Detalles Bibliográficos
Autores principales: Ammari, Meryem, Presumey, Jessy, Ponsolles, Clara, Roussignol, Gautier, Roubert, Christine, Escriou, Virginie, Toupet, Karine, Mausset-Bonnefont, Anne-Laure, Cren, Maïlys, Robin, Maxime, Georgel, Philippe, Nehmar, Ramzi, Taams, Leonie, Grün, Joachim, Grützkau, Andrea, Häupl, Thomas, Pers, Yves-Marie, Jorgensen, Christian, Duroux-Richard, Isabelle, Courties, Gabriel, Apparailly, Florence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299444/
https://www.ncbi.nlm.nih.gov/pubmed/30613275
http://dx.doi.org/10.7150/thno.29313