Large-scale pharmacogenomics based drug discovery for ITGB3 dependent chemoresistance in mesenchymal lung cancer

Even when targets responsible for chemoresistance are identified, drug development is often hampered due to the poor druggability of these proteins. We systematically analyzed therapy-resistance with a large-scale cancer cell transcriptome and drug-response datasets and predicted the candidate drugs...

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Detalles Bibliográficos
Autores principales: Hong, Soon-Ki, Lee, Haeseung, Kwon, Ok-Seon, Song, Na-Young, Lee, Hyo-Ju, Kang, Seungmin, Kim, Jeong-Hwan, Kim, Mirang, Kim, Wankyu, Cha, Hyuk-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299529/
https://www.ncbi.nlm.nih.gov/pubmed/30563517
http://dx.doi.org/10.1186/s12943-018-0924-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299529/
https://www.ncbi.nlm.nih.gov/pubmed/30563517
http://dx.doi.org/10.1186/s12943-018-0924-8

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