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Assessment of inpatient antibiotic use in Halibet National Referral Hospital using WHO indicators: a retrospective study

OBJECTIVE: Inappropriate use of antibiotics in primary care and hospital settings is a major contributing factor to the spread of antibiotic resistance. Many microorganisms were tested in Eritrea and have proven resistant to ampicillin. The aim of this study was to investigate the prescription patte...

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Detalles Bibliográficos
Autores principales: Amaha, Nebyu Daniel, Berhe, Yohana Haile, Kaushik, Atul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299551/
https://www.ncbi.nlm.nih.gov/pubmed/30563558
http://dx.doi.org/10.1186/s13104-018-4000-7
Descripción
Sumario:OBJECTIVE: Inappropriate use of antibiotics in primary care and hospital settings is a major contributing factor to the spread of antibiotic resistance. Many microorganisms were tested in Eritrea and have proven resistant to ampicillin. The aim of this study was to investigate the prescription pattern, hospital indicator and patient care indicator of antibiotics among hospitalized patients in Halibet National Referral Hospital, Asmara, Eritrea. RESULTS: The data on prescription patterns showed 79% of hospitalizations had at least one antibiotic prescribed and on average 1.29 antibiotics were prescribed per hospitalization; prescribing using generic name was at 97%; all (100%) of the antibiotics were prescribed from the Eritrean National List of Medicines. On average an antibiotic was prescribed for 6.36 days (SD = 6.06). Ampicillin was the most commonly prescribed antibiotic (42.1%) and parenteral was the most common route prescribed (81.4%). The data on hospital indicators showed key antibiotics were out of stock on average for 78.18 days; 87.5% of key antibiotics were available on the day of the study. The data on patient care indicator showed patients taking antibiotics stayed in the hospital for 9.97 days (± 7.33 days). ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s13104-018-4000-7) contains supplementary material, which is available to authorized users.