Identification of the decumbenone biosynthetic gene cluster in Penicillium decumbens and the importance for production of calbistrin

BACKGROUND: Filamentous fungi are important producers of secondary metabolites, low molecular weight molecules that often have bioactive properties. Calbistrin A is a secondary metabolite with an interesting structure that was recently found to have bioactivity against leukemia cells. It consists of...

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Detalles Bibliográficos
Autores principales: Grijseels, Sietske, Pohl, Carsten, Nielsen, Jens Christian, Wasil, Zahida, Nygård, Yvonne, Nielsen, Jens, Frisvad, Jens C., Nielsen, Kristian Fog, Workman, Mhairi, Larsen, Thomas Ostenfeld, Driessen, Arnold J. M., Frandsen, Rasmus John Normand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299560/
https://www.ncbi.nlm.nih.gov/pubmed/30598828
http://dx.doi.org/10.1186/s40694-018-0063-4

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