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A novel detection methodology for HER2 protein quantitation in formalin-fixed, paraffin embedded clinical samples using fluorescent nanoparticles: an analytical and clinical validation study
BACKGROUND: Clinical assays for the assessment of the human epidermal growth factor receptor-2 (HER2) status in breast cancer include immunohistochemistry (IHC) and in situ hybridization (ISH), both of which have limitations. Recent studies have suggested that a more quantitative approach to the mea...
Autores principales: | Hicks, David G., Buscaglia, Brandon, Goda, Hideki, McMahon, Loralee, Natori, Takako, Turner, Bradley, Soukiazian, Armen, Okada, Hisatake, Nakano, Yasushi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299600/ https://www.ncbi.nlm.nih.gov/pubmed/30563489 http://dx.doi.org/10.1186/s12885-018-5172-1 |
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