Tumor cell-released autophagosomes (TRAPs) promote immunosuppression through induction of M2-like macrophages with increased expression of PD-L1

BACKGROUND: Tumor-associated macrophages (TAMs) facilitate tumor progression via establishment of an immunosuppressive tumor microenvironment (TME). However, it is poorly understood how tumor cells could functionally modulate TAMs. Our previous work indicated that tumor cell-released autophagosomes...

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Detalles Bibliográficos
Autores principales: Wen, Zhi-Fa, Liu, Hongxiang, Gao, Rong, Zhou, Meng, Ma, Jie, Zhang, Yue, Zhao, Jinjin, Chen, Yongqiang, Zhang, Tianyu, Huang, Fang, Pan, Ning, Zhang, Jinping, Fox, Bernard A., Hu, Hong-Ming, Wang, Li-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299637/
https://www.ncbi.nlm.nih.gov/pubmed/30563569
http://dx.doi.org/10.1186/s40425-018-0452-5

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