Mass drug administration for malaria elimination: do we understand the settings well enough?

Mass drug administration (MDA) of antimalarials has re-emerged as a recommended tool for interrupting malaria transmission, but evidence from low endemicity settings is scarce. A trial in Zanzibar found that two rounds of MDA made no significant impact on malaria incidence, and many questions on the...

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Detalles Bibliográficos
Autores principales: Hetzel, Manuel W., Genton, Blaise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299650/
https://www.ncbi.nlm.nih.gov/pubmed/30563509
http://dx.doi.org/10.1186/s12916-018-1230-4
Descripción
Sumario:Mass drug administration (MDA) of antimalarials has re-emerged as a recommended tool for interrupting malaria transmission, but evidence from low endemicity settings is scarce. A trial in Zanzibar found that two rounds of MDA made no significant impact on malaria incidence, and many questions on the optimal mode and setting for implementing MDA remain unanswered. A more thorough understanding of local sources and drivers of transmission, and a better toolbox for evaluating interventions in near-elimination settings are essential. Please see related research article: https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-018-1202-8.

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