Mass drug administration for malaria elimination: do we understand the settings well enough?

Mass drug administration (MDA) of antimalarials has re-emerged as a recommended tool for interrupting malaria transmission, but evidence from low endemicity settings is scarce. A trial in Zanzibar found that two rounds of MDA made no significant impact on malaria incidence, and many questions on the...

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Detalles Bibliográficos
Autores principales: Hetzel, Manuel W., Genton, Blaise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299650/
https://www.ncbi.nlm.nih.gov/pubmed/30563509
http://dx.doi.org/10.1186/s12916-018-1230-4
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author Hetzel, Manuel W.
Genton, Blaise
author_facet Hetzel, Manuel W.
Genton, Blaise
author_sort Hetzel, Manuel W.
collection PubMed
description Mass drug administration (MDA) of antimalarials has re-emerged as a recommended tool for interrupting malaria transmission, but evidence from low endemicity settings is scarce. A trial in Zanzibar found that two rounds of MDA made no significant impact on malaria incidence, and many questions on the optimal mode and setting for implementing MDA remain unanswered. A more thorough understanding of local sources and drivers of transmission, and a better toolbox for evaluating interventions in near-elimination settings are essential. Please see related research article: https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-018-1202-8.
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spelling pubmed-62996502018-12-20 Mass drug administration for malaria elimination: do we understand the settings well enough? Hetzel, Manuel W. Genton, Blaise BMC Med Commentary Mass drug administration (MDA) of antimalarials has re-emerged as a recommended tool for interrupting malaria transmission, but evidence from low endemicity settings is scarce. A trial in Zanzibar found that two rounds of MDA made no significant impact on malaria incidence, and many questions on the optimal mode and setting for implementing MDA remain unanswered. A more thorough understanding of local sources and drivers of transmission, and a better toolbox for evaluating interventions in near-elimination settings are essential. Please see related research article: https://bmcmedicine.biomedcentral.com/articles/10.1186/s12916-018-1202-8. BioMed Central 2018-12-19 /pmc/articles/PMC6299650/ /pubmed/30563509 http://dx.doi.org/10.1186/s12916-018-1230-4 Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Commentary
Hetzel, Manuel W.
Genton, Blaise
Mass drug administration for malaria elimination: do we understand the settings well enough?
title Mass drug administration for malaria elimination: do we understand the settings well enough?
title_full Mass drug administration for malaria elimination: do we understand the settings well enough?
title_fullStr Mass drug administration for malaria elimination: do we understand the settings well enough?
title_full_unstemmed Mass drug administration for malaria elimination: do we understand the settings well enough?
title_short Mass drug administration for malaria elimination: do we understand the settings well enough?
title_sort mass drug administration for malaria elimination: do we understand the settings well enough?
topic Commentary
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299650/
https://www.ncbi.nlm.nih.gov/pubmed/30563509
http://dx.doi.org/10.1186/s12916-018-1230-4
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