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CD44ICD promotes breast cancer stemness via PFKFB4-mediated glucose metabolism

CD44 is a single-pass cell surface glycoprotein that is distinguished as the first molecule used to identify cancer stem cells in solid tumors based on its expression. In this regard, the CD44(high) cell population demonstrates not only the ability to regenerate a heterogeneous tumor, but also the a...

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Detalles Bibliográficos
Autores principales: Gao, Ruifang, Li, Dan, Xun, Jing, Zhou, Wei, Li, Jun, Wang, Juan, Liu, Chen, Li, Xiru, Shen, Wenzhi, Qiao, Huan, Stupack, Dwayne G., Luo, Na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299690/
https://www.ncbi.nlm.nih.gov/pubmed/30613295
http://dx.doi.org/10.7150/thno.28721