Deficiency of TLR4 ameliorates hypoperfusion-induced brain pathology

Microglial inflammatory activation contributes to chronic cerebral hypoperfusion-induced brain pathology. This editorial highlights a study by Qin et al. (Theranostics 2018; 8(19):5434-5451. doi:10.7150/thno.27882) that deficiency of TLR4 attenuates cognitive dysfunction and white matter injury by r...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Yang, Fassbender, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2018
Materias:
Editorial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299697/
https://www.ncbi.nlm.nih.gov/pubmed/30613303
http://dx.doi.org/10.7150/thno.30953
_version_ 1783381541954519040
author Liu, Yang
Fassbender, Klaus
author_facet Liu, Yang
Fassbender, Klaus
author_sort Liu, Yang
collection PubMed
description Microglial inflammatory activation contributes to chronic cerebral hypoperfusion-induced brain pathology. This editorial highlights a study by Qin et al. (Theranostics 2018; 8(19):5434-5451. doi:10.7150/thno.27882) that deficiency of TLR4 attenuates cognitive dysfunction and white matter injury by reducing autophagy and pro-inflammatory activation in microglia.
format Online
Article
Text
id pubmed-6299697
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Ivyspring International Publisher
record_format MEDLINE/PubMed
spelling pubmed-62996972019-01-04 Deficiency of TLR4 ameliorates hypoperfusion-induced brain pathology Liu, Yang Fassbender, Klaus Theranostics Editorial Microglial inflammatory activation contributes to chronic cerebral hypoperfusion-induced brain pathology. This editorial highlights a study by Qin et al. (Theranostics 2018; 8(19):5434-5451. doi:10.7150/thno.27882) that deficiency of TLR4 attenuates cognitive dysfunction and white matter injury by reducing autophagy and pro-inflammatory activation in microglia. Ivyspring International Publisher 2018-12-01 /pmc/articles/PMC6299697/ /pubmed/30613303 http://dx.doi.org/10.7150/thno.30953 Text en © Ivyspring International Publisher This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY-NC) license (https://creativecommons.org/licenses/by-nc/4.0/). See http://ivyspring.com/terms for full terms and conditions.
spellingShingle Editorial
Liu, Yang
Fassbender, Klaus
Deficiency of TLR4 ameliorates hypoperfusion-induced brain pathology
title Deficiency of TLR4 ameliorates hypoperfusion-induced brain pathology
title_full Deficiency of TLR4 ameliorates hypoperfusion-induced brain pathology
title_fullStr Deficiency of TLR4 ameliorates hypoperfusion-induced brain pathology
title_full_unstemmed Deficiency of TLR4 ameliorates hypoperfusion-induced brain pathology
title_short Deficiency of TLR4 ameliorates hypoperfusion-induced brain pathology
title_sort deficiency of tlr4 ameliorates hypoperfusion-induced brain pathology
topic Editorial
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299697/
https://www.ncbi.nlm.nih.gov/pubmed/30613303
http://dx.doi.org/10.7150/thno.30953
work_keys_str_mv AT liuyang deficiencyoftlr4ameliorateshypoperfusioninducedbrainpathology
AT fassbenderklaus deficiencyoftlr4ameliorateshypoperfusioninducedbrainpathology

Ejemplares similares