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Anti-tumor macrophages activated by ferumoxytol combined or surface-functionalized with the TLR3 agonist poly (I : C) promote melanoma regression

Macrophages orchestrate inflammation and control the promotion or inhibition of tumors and metastasis. Ferumoxytol (FMT), a clinically approved iron oxide nanoparticle, possesses anti-tumor therapeutic potential by inducing pro-inflammatory macrophage polarization. Toll-like receptor 3 (TLR3) activa...

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Detalles Bibliográficos
Autores principales:	zhao, Jiaojiao, Zhang, Zhengkui, Xue, Yaxian, Wang, Guoqun, Cheng, Yuan, Pan, Yuchen, Zhao, Shuli, Hou, Yayi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299704/ https://www.ncbi.nlm.nih.gov/pubmed/30613299 http://dx.doi.org/10.7150/thno.29746

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