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An unusual case of tuberous sclerosis incidentally discovered in adulthood: case report and review of the literature

Tuberous sclerosis (TS) is a relatively rare multi-organ disorder generally diagnosed in infancy and described as a clinical triad of sebaceous adenoma, mental retardation, and seizures. Angiomyolipoma (AML) is the most common benign renal tumor usually found incidentally as a solitary small echogen...

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Autores principales: Ferrara, Dolores, Vallone, Gianfranco, Tedeschi, Enrico, Ponsiglione, Andrea, Stanzione, Arnaldo, Pisani, Antonio, Imbriaco, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299912/
https://www.ncbi.nlm.nih.gov/pubmed/30619624
http://dx.doi.org/10.1177/2058460118806328
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author Ferrara, Dolores
Vallone, Gianfranco
Tedeschi, Enrico
Ponsiglione, Andrea
Stanzione, Arnaldo
Pisani, Antonio
Imbriaco, Massimo
author_facet Ferrara, Dolores
Vallone, Gianfranco
Tedeschi, Enrico
Ponsiglione, Andrea
Stanzione, Arnaldo
Pisani, Antonio
Imbriaco, Massimo
author_sort Ferrara, Dolores
collection PubMed
description Tuberous sclerosis (TS) is a relatively rare multi-organ disorder generally diagnosed in infancy and described as a clinical triad of sebaceous adenoma, mental retardation, and seizures. Angiomyolipoma (AML) is the most common benign renal tumor usually found incidentally as a solitary small echogenic lesion on grayscale ultrasound. Less commonly, it is part of the TS complex and is seen as multiple lesions in both kidneys. We describe an unusual case of TS incidentally diagnosed in a 37-year-old female patient with several and bilateral renal AMLs and a single cortical–subcortical tuber in the right parieto-occipital cerebral lobe.
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spelling pubmed-62999122019-01-07 An unusual case of tuberous sclerosis incidentally discovered in adulthood: case report and review of the literature Ferrara, Dolores Vallone, Gianfranco Tedeschi, Enrico Ponsiglione, Andrea Stanzione, Arnaldo Pisani, Antonio Imbriaco, Massimo Acta Radiol Open Case Report Tuberous sclerosis (TS) is a relatively rare multi-organ disorder generally diagnosed in infancy and described as a clinical triad of sebaceous adenoma, mental retardation, and seizures. Angiomyolipoma (AML) is the most common benign renal tumor usually found incidentally as a solitary small echogenic lesion on grayscale ultrasound. Less commonly, it is part of the TS complex and is seen as multiple lesions in both kidneys. We describe an unusual case of TS incidentally diagnosed in a 37-year-old female patient with several and bilateral renal AMLs and a single cortical–subcortical tuber in the right parieto-occipital cerebral lobe. SAGE Publications 2018-12-06 /pmc/articles/PMC6299912/ /pubmed/30619624 http://dx.doi.org/10.1177/2058460118806328 Text en © The Foundation Acta Radiologica 2018 http://creativecommons.org/licenses/by-nc/4.0/ Creative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Ferrara, Dolores
Vallone, Gianfranco
Tedeschi, Enrico
Ponsiglione, Andrea
Stanzione, Arnaldo
Pisani, Antonio
Imbriaco, Massimo
An unusual case of tuberous sclerosis incidentally discovered in adulthood: case report and review of the literature
title An unusual case of tuberous sclerosis incidentally discovered in adulthood: case report and review of the literature
title_full An unusual case of tuberous sclerosis incidentally discovered in adulthood: case report and review of the literature
title_fullStr An unusual case of tuberous sclerosis incidentally discovered in adulthood: case report and review of the literature
title_full_unstemmed An unusual case of tuberous sclerosis incidentally discovered in adulthood: case report and review of the literature
title_short An unusual case of tuberous sclerosis incidentally discovered in adulthood: case report and review of the literature
title_sort unusual case of tuberous sclerosis incidentally discovered in adulthood: case report and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299912/
https://www.ncbi.nlm.nih.gov/pubmed/30619624
http://dx.doi.org/10.1177/2058460118806328
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