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Therapeutic benefits of Indole-3-Carbinol in adjuvant-induced arthritis and its protective effect against methotrexate induced-hepatic toxicity

BACKGROUND: Rheumatoid arthritis (RA) being an incapacitating disease requires early effective intervention. Considering Methotrexate (MTX)- the first line of treatment for RA- intoxicates the liver; therefore, alternative therapies with similar efficacy yet lower cytotoxicity are desired. Indole-3-...

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Detalles Bibliográficos
Autores principales:	Hasan, Hiba, Ismail, Hanan, El-Orfali, Youmna, Khawaja, Ghada
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6299996/ https://www.ncbi.nlm.nih.gov/pubmed/30567538 http://dx.doi.org/10.1186/s12906-018-2408-1

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