Cerebral infarcts associated with adenomyosis: a rare risk factor for stroke in middle-aged women: a case series

BACKGROUND: Adenomyosis is a benign disease with elevated CA125 level. CASE PRESENTATION: We report 3 cases with adenomyosis who developed ischemic stroke during menstruation. The levels of CA125, CA19–9, and D-dimer were elevated, which dropped markedly after the menstrual phase. The development of...

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Autores principales: Yin, Xinzhen, Wu, Jimin, Song, Shuijiang, Zhang, Baorong, Chen, Yanxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300031/
https://www.ncbi.nlm.nih.gov/pubmed/30567506
http://dx.doi.org/10.1186/s12883-018-1213-2
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author Yin, Xinzhen
Wu, Jimin
Song, Shuijiang
Zhang, Baorong
Chen, Yanxing
author_facet Yin, Xinzhen
Wu, Jimin
Song, Shuijiang
Zhang, Baorong
Chen, Yanxing
author_sort Yin, Xinzhen
collection PubMed
description BACKGROUND: Adenomyosis is a benign disease with elevated CA125 level. CASE PRESENTATION: We report 3 cases with adenomyosis who developed ischemic stroke during menstruation. The levels of CA125, CA19–9, and D-dimer were elevated, which dropped markedly after the menstrual phase. The development of nonbacterial thrombotic endocarditis (NBTE) and stenosis of the cerebral arteries associated with hypercoagulable state and the hyperviscosity nature of the mucinous protein may be the underlying mechanisms. CONCLUSION: Our report suggests that adenomyosis might be a risk factor for ischemic stroke in middle-aged patients.
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spelling pubmed-63000312018-12-20 Cerebral infarcts associated with adenomyosis: a rare risk factor for stroke in middle-aged women: a case series Yin, Xinzhen Wu, Jimin Song, Shuijiang Zhang, Baorong Chen, Yanxing BMC Neurol Case Report BACKGROUND: Adenomyosis is a benign disease with elevated CA125 level. CASE PRESENTATION: We report 3 cases with adenomyosis who developed ischemic stroke during menstruation. The levels of CA125, CA19–9, and D-dimer were elevated, which dropped markedly after the menstrual phase. The development of nonbacterial thrombotic endocarditis (NBTE) and stenosis of the cerebral arteries associated with hypercoagulable state and the hyperviscosity nature of the mucinous protein may be the underlying mechanisms. CONCLUSION: Our report suggests that adenomyosis might be a risk factor for ischemic stroke in middle-aged patients. BioMed Central 2018-12-19 /pmc/articles/PMC6300031/ /pubmed/30567506 http://dx.doi.org/10.1186/s12883-018-1213-2 Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Yin, Xinzhen
Wu, Jimin
Song, Shuijiang
Zhang, Baorong
Chen, Yanxing
Cerebral infarcts associated with adenomyosis: a rare risk factor for stroke in middle-aged women: a case series
title Cerebral infarcts associated with adenomyosis: a rare risk factor for stroke in middle-aged women: a case series
title_full Cerebral infarcts associated with adenomyosis: a rare risk factor for stroke in middle-aged women: a case series
title_fullStr Cerebral infarcts associated with adenomyosis: a rare risk factor for stroke in middle-aged women: a case series
title_full_unstemmed Cerebral infarcts associated with adenomyosis: a rare risk factor for stroke in middle-aged women: a case series
title_short Cerebral infarcts associated with adenomyosis: a rare risk factor for stroke in middle-aged women: a case series
title_sort cerebral infarcts associated with adenomyosis: a rare risk factor for stroke in middle-aged women: a case series
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300031/
https://www.ncbi.nlm.nih.gov/pubmed/30567506
http://dx.doi.org/10.1186/s12883-018-1213-2
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