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Childhood adversities are different in Schizophrenic Spectrum Disorders, Bipolar Disorder and Major Depressive Disorder

BACKGROUND: Research has shown that a history of childhood adversities is common in patients with psychiatric disorders but few studies have investigated links between specific types of adversity and specific psychiatric disorders. METHODS: We investigated the frequency of early childhood adversitie...

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Autores principales: Bruni, Antonella, Carbone, Elvira Anna, Pugliese, Valentina, Aloi, Matteo, Calabrò, Giuseppina, Cerminara, Gregorio, Segura-García, Cristina, De Fazio, Pasquale
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300034/
https://www.ncbi.nlm.nih.gov/pubmed/30567512
http://dx.doi.org/10.1186/s12888-018-1972-8
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author Bruni, Antonella
Carbone, Elvira Anna
Pugliese, Valentina
Aloi, Matteo
Calabrò, Giuseppina
Cerminara, Gregorio
Segura-García, Cristina
De Fazio, Pasquale
author_facet Bruni, Antonella
Carbone, Elvira Anna
Pugliese, Valentina
Aloi, Matteo
Calabrò, Giuseppina
Cerminara, Gregorio
Segura-García, Cristina
De Fazio, Pasquale
author_sort Bruni, Antonella
collection PubMed
description BACKGROUND: Research has shown that a history of childhood adversities is common in patients with psychiatric disorders but few studies have investigated links between specific types of adversity and specific psychiatric disorders. METHODS: We investigated the frequency of early childhood adversities in a sample consisting of 91 patients with diagnosis of schizophrenic spectrum disorders (SSD), 74 patients with bipolar disorder (BD), 83 patients with major depressive disorder (MDD) and 85 healthy controls and sought to identify adverse early childhood life events that predict the development of major psychiatric disorders. The Childhood Experiences of Care and Abuse questionnaire was used to collect data on traumatic experiences occurring before the age of 17 years and comprehensive demographic data were also collected. The data were analyzed with chi-squared tests, t-tests, post-hoc and logistic regression. RESULTS: Maternal absence/loss and economic difficulties in the early life were more prevalent in the BD group than other groups. Escape from home, cannabis abuse, psychological abuse, physical abuse and loneliness were more frequent in the SSD group than in other groups. Paternal absence, neglect of core needs, serious familial tension and absence of adult and peer confidants were all less common in the HC group than in the other groups. The regression model confirmed that different types of adversities play a crucial role in the development of the three investigated disorders. CONCLUSIONS: Our results support that SSD, BD and MDD are associated to different childhood adversities. This suggests that psychosocial interventions that reduce the incidence of these early life adversities might reduce the incidence of severe and disabling psychiatric disorders. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s12888-018-1972-8) contains supplementary material, which is available to authorized users.
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spelling pubmed-63000342018-12-20 Childhood adversities are different in Schizophrenic Spectrum Disorders, Bipolar Disorder and Major Depressive Disorder Bruni, Antonella Carbone, Elvira Anna Pugliese, Valentina Aloi, Matteo Calabrò, Giuseppina Cerminara, Gregorio Segura-García, Cristina De Fazio, Pasquale BMC Psychiatry Research Article BACKGROUND: Research has shown that a history of childhood adversities is common in patients with psychiatric disorders but few studies have investigated links between specific types of adversity and specific psychiatric disorders. METHODS: We investigated the frequency of early childhood adversities in a sample consisting of 91 patients with diagnosis of schizophrenic spectrum disorders (SSD), 74 patients with bipolar disorder (BD), 83 patients with major depressive disorder (MDD) and 85 healthy controls and sought to identify adverse early childhood life events that predict the development of major psychiatric disorders. The Childhood Experiences of Care and Abuse questionnaire was used to collect data on traumatic experiences occurring before the age of 17 years and comprehensive demographic data were also collected. The data were analyzed with chi-squared tests, t-tests, post-hoc and logistic regression. RESULTS: Maternal absence/loss and economic difficulties in the early life were more prevalent in the BD group than other groups. Escape from home, cannabis abuse, psychological abuse, physical abuse and loneliness were more frequent in the SSD group than in other groups. Paternal absence, neglect of core needs, serious familial tension and absence of adult and peer confidants were all less common in the HC group than in the other groups. The regression model confirmed that different types of adversities play a crucial role in the development of the three investigated disorders. CONCLUSIONS: Our results support that SSD, BD and MDD are associated to different childhood adversities. This suggests that psychosocial interventions that reduce the incidence of these early life adversities might reduce the incidence of severe and disabling psychiatric disorders. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1186/s12888-018-1972-8) contains supplementary material, which is available to authorized users. BioMed Central 2018-12-19 /pmc/articles/PMC6300034/ /pubmed/30567512 http://dx.doi.org/10.1186/s12888-018-1972-8 Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Bruni, Antonella
Carbone, Elvira Anna
Pugliese, Valentina
Aloi, Matteo
Calabrò, Giuseppina
Cerminara, Gregorio
Segura-García, Cristina
De Fazio, Pasquale
Childhood adversities are different in Schizophrenic Spectrum Disorders, Bipolar Disorder and Major Depressive Disorder
title Childhood adversities are different in Schizophrenic Spectrum Disorders, Bipolar Disorder and Major Depressive Disorder
title_full Childhood adversities are different in Schizophrenic Spectrum Disorders, Bipolar Disorder and Major Depressive Disorder
title_fullStr Childhood adversities are different in Schizophrenic Spectrum Disorders, Bipolar Disorder and Major Depressive Disorder
title_full_unstemmed Childhood adversities are different in Schizophrenic Spectrum Disorders, Bipolar Disorder and Major Depressive Disorder
title_short Childhood adversities are different in Schizophrenic Spectrum Disorders, Bipolar Disorder and Major Depressive Disorder
title_sort childhood adversities are different in schizophrenic spectrum disorders, bipolar disorder and major depressive disorder
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300034/
https://www.ncbi.nlm.nih.gov/pubmed/30567512
http://dx.doi.org/10.1186/s12888-018-1972-8
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