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In vivo protective effects of chlorogenic acid against triptolide-induced hepatotoxicity and its mechanism

Context: Triptolide (TP) has outstanding biological activities, but it induces toxicities, particular hepatotoxicity, severely limiting its clinical application. Chlorogenic acid (CGA) has prominently medicinal and nutritional values. However, until now, it is not known whether CGA could mitigate TP...

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Detalles Bibliográficos
Autores principales: Wang, Jun-Ming, Chen, Rong-Xing, Zhang, Lu-Lu, Ding, Ning-Ning, Liu, Chen, Cui, Ying, Cheng, Yong-Xian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300082/
https://www.ncbi.nlm.nih.gov/pubmed/31070533
http://dx.doi.org/10.1080/13880209.2018.1527370