Alkaline phosphatase levels of murine pre-osteoblastic cells on anodized and annealed titanium surfaces

PURPOSE: This study aimed to evaluate the initial adhesion morphology and alkaline phosphatase (ALP) activity of murine pre-osteoblastic MC3T3-E1 cells cultured on anatase/rutile mixed-phase TiO(2) thin films with photocatalytical activity with previously confirmed antibacterial properties. MATERIAL...

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Detalles Bibliográficos
Autores principales: Yeniyol, Sinem, Ricci, John Lawrence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Istanbul University Faculty of Dentistry 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300123/
https://www.ncbi.nlm.nih.gov/pubmed/30574594
http://dx.doi.org/10.26650/eor.2018.78387
Descripción
Sumario:PURPOSE: This study aimed to evaluate the initial adhesion morphology and alkaline phosphatase (ALP) activity of murine pre-osteoblastic MC3T3-E1 cells cultured on anatase/rutile mixed-phase TiO(2) thin films with photocatalytical activity with previously confirmed antibacterial properties. MATERIALS AND METHODS: Anatase/rutile mixed-phase TiO(2) thin films fabricated by anodization and annealing of cpTi were used to culture MC3T3-E1 cells to evaluate the initial cellular adhesion morphology and ALP activity in vitro. RESULTS: Compared with MC3T3-E1 cells cultured on cpTi substrates and the control group, cells cultured on anatase/rutile mixed-phase TiO(2) thin films exhibited similar ALP levels after cell culture day 9. CONCLUSION: Anodizing and annealing processes fabricate multifunctional surfaces on cpTi with improved osteogenic properties for implants.

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