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Swall-E: A robotic in-vitro simulation of human swallowing

Swallowing is a complex physiological function that can be studied through medical imagery techniques such as videofluoroscopy (VFS), dynamic magnetic resonance imagery (MRI) and fiberoptic endoscopic evaluation of swallowing (FEES). VFS is the gold standard although it exposes the subjects to radia...

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Autores principales: Fujiso, Yo, Perrin, Nicolas, van der Giessen, Julian, Vrana, Nihal Engin, Neveu, Fabrice, Woisard, Virginie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300196/
https://www.ncbi.nlm.nih.gov/pubmed/30566460
http://dx.doi.org/10.1371/journal.pone.0208193
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author Fujiso, Yo
Perrin, Nicolas
van der Giessen, Julian
Vrana, Nihal Engin
Neveu, Fabrice
Woisard, Virginie
author_facet Fujiso, Yo
Perrin, Nicolas
van der Giessen, Julian
Vrana, Nihal Engin
Neveu, Fabrice
Woisard, Virginie
author_sort Fujiso, Yo
collection PubMed
description Swallowing is a complex physiological function that can be studied through medical imagery techniques such as videofluoroscopy (VFS), dynamic magnetic resonance imagery (MRI) and fiberoptic endoscopic evaluation of swallowing (FEES). VFS is the gold standard although it exposes the subjects to radiations. In-vitro modeling of human swallowing has been conducted with limited results so far. Some experiments were reported on robotic reproduction of oral and esophageal phases of swallowing, but high fidelity reproduction of pharyngeal phase of swallowing has not been reported yet. To that end, we designed and developed a robotic simulator of the pharyngeal phase of human swallowing named Swall-E. 17 actuators integrated in the robot enable the mimicking of important physiological mechanisms occurring during the pharyngeal swallowing, such as the vocal fold closure, laryngeal elevation or epiglottis tilt. Moreover, the associated computer interface allows a control of the actuation of these mechanisms at a spatio-temporal accuracy of 0.025 mm and 20 ms. In this study preliminary experiments of normal pharyngeal swallowing simulated on Swall-E are presented. These experiments show that a 10 ml thick bolus can be swallowed by the robot in less than 1 s without any aspiration of bolus material into the synthetic anatomical laryngo-tracheal conduit.
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spelling pubmed-63001962018-12-28 Swall-E: A robotic in-vitro simulation of human swallowing Fujiso, Yo Perrin, Nicolas van der Giessen, Julian Vrana, Nihal Engin Neveu, Fabrice Woisard, Virginie PLoS One Research Article Swallowing is a complex physiological function that can be studied through medical imagery techniques such as videofluoroscopy (VFS), dynamic magnetic resonance imagery (MRI) and fiberoptic endoscopic evaluation of swallowing (FEES). VFS is the gold standard although it exposes the subjects to radiations. In-vitro modeling of human swallowing has been conducted with limited results so far. Some experiments were reported on robotic reproduction of oral and esophageal phases of swallowing, but high fidelity reproduction of pharyngeal phase of swallowing has not been reported yet. To that end, we designed and developed a robotic simulator of the pharyngeal phase of human swallowing named Swall-E. 17 actuators integrated in the robot enable the mimicking of important physiological mechanisms occurring during the pharyngeal swallowing, such as the vocal fold closure, laryngeal elevation or epiglottis tilt. Moreover, the associated computer interface allows a control of the actuation of these mechanisms at a spatio-temporal accuracy of 0.025 mm and 20 ms. In this study preliminary experiments of normal pharyngeal swallowing simulated on Swall-E are presented. These experiments show that a 10 ml thick bolus can be swallowed by the robot in less than 1 s without any aspiration of bolus material into the synthetic anatomical laryngo-tracheal conduit. Public Library of Science 2018-12-19 /pmc/articles/PMC6300196/ /pubmed/30566460 http://dx.doi.org/10.1371/journal.pone.0208193 Text en © 2018 Fujiso et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Fujiso, Yo
Perrin, Nicolas
van der Giessen, Julian
Vrana, Nihal Engin
Neveu, Fabrice
Woisard, Virginie
Swall-E: A robotic in-vitro simulation of human swallowing
title Swall-E: A robotic in-vitro simulation of human swallowing
title_full Swall-E: A robotic in-vitro simulation of human swallowing
title_fullStr Swall-E: A robotic in-vitro simulation of human swallowing
title_full_unstemmed Swall-E: A robotic in-vitro simulation of human swallowing
title_short Swall-E: A robotic in-vitro simulation of human swallowing
title_sort swall-e: a robotic in-vitro simulation of human swallowing
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300196/
https://www.ncbi.nlm.nih.gov/pubmed/30566460
http://dx.doi.org/10.1371/journal.pone.0208193
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