Increased breadth of HIV-1 neutralization achieved by diverse antibody clones each with limited neutralization breadth

Broadly neutralizing antibodies (bNAbs) are rarely elicited by current human immunodeficiency virus type 1 (HIV-1) vaccine designs, but the presence of bNAbs in naturally infected individuals may be associated with high plasma viral loads, suggesting that the magnitude, duration, and diversity of vi...

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Detalles Bibliográficos
Autores principales: Chukwuma, Valentine U., Kose, Nurgun, Sather, D. Noah, Sapparapu, Gopal, Falk, Rachel, King, Hannah, Singh, Vidisha, Lampley, Rebecca, Malherbe, Delphine C., Ditto, Noah T., Sullivan, Jonathan T., Barnes, Trevor, Doranz, Benjamin J., Labranche, Celia C., Montefiori, David C., Kalams, Spyros A., Haigwood, Nancy L., Crowe, James E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300260/
https://www.ncbi.nlm.nih.gov/pubmed/30566528
http://dx.doi.org/10.1371/journal.pone.0209437

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