Cargando…
New insights of polyamine metabolism in testicular physiology: A role of ornithine decarboxylase antizyme inhibitor 2 (AZIN2) in the modulation of testosterone levels and sperm motility
The specific role of polyamines in the testis physiology is not fully understood. Antizymes (OAZs) and antizyme inhibitors (AZINs) are modulators of ornithine decarboxylase (ODC), a key enzyme in polyamine biosynthesis and polyamine uptake. Although the three known OAZs are expressed in the testis,...
Autores principales: | Lambertos, Ana, Ramos-Molina, Bruno, López-Contreras, Andrés J., Cremades, Asunción, Peñafiel, Rafael |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300296/ https://www.ncbi.nlm.nih.gov/pubmed/30566531 http://dx.doi.org/10.1371/journal.pone.0209202 |
Ejemplares similares
-
Structural and degradative aspects of ornithine decarboxylase antizyme inhibitor 2
por: Ramos-Molina, Bruno, et al.
Publicado: (2014) -
Polyamine biosynthesis in Xenopus laevis: the xlAZIN2/xlODC2 gene encodes a lysine/ornithine decarboxylase
por: Lambertos, Ana, et al.
Publicado: (2019) -
Polyamines directly promote antizyme-mediated degradation of ornithine decarboxylase by the proteasome
por: Beenukumar, R. R., et al.
Publicado: (2015) -
Antizyme Inhibitors in Polyamine Metabolism and Beyond: Physiopathological Implications
por: Ramos-Molina, Bruno, et al.
Publicado: (2018) -
Structural basis of Ornithine Decarboxylase inactivation and accelerated degradation by polyamine sensor Antizyme1
por: Wu, Donghui, et al.
Publicado: (2015)