Large-scale genome-wide meta-analysis of polycystic ovary syndrome suggests shared genetic architecture for different diagnosis criteria

Polycystic ovary syndrome (PCOS) is a disorder characterized by hyperandrogenism, ovulatory dysfunction and polycystic ovarian morphology. Affected women frequently have metabolic disturbances including insulin resistance and dysregulation of glucose homeostasis. PCOS is diagnosed with two different...

Descripción completa

Detalles Bibliográficos
Autores principales: Day, Felix, Karaderi, Tugce, Jones, Michelle R., Meun, Cindy, He, Chunyan, Drong, Alex, Kraft, Peter, Lin, Nan, Huang, Hongyan, Broer, Linda, Magi, Reedik, Saxena, Richa, Laisk, Triin, Urbanek, Margrit, Hayes, M. Geoffrey, Thorleifsson, Gudmar, Fernandez-Tajes, Juan, Mahajan, Anubha, Mullin, Benjamin H., Stuckey, Bronwyn G. A., Spector, Timothy D., Wilson, Scott G., Goodarzi, Mark O., Davis, Lea, Obermayer-Pietsch, Barbara, Uitterlinden, André G., Anttila, Verneri, Neale, Benjamin M., Jarvelin, Marjo-Riitta, Fauser, Bart, Kowalska, Irina, Visser, Jenny A., Andersen, Marianne, Ong, Ken, Stener-Victorin, Elisabet, Ehrmann, David, Legro, Richard S., Salumets, Andres, McCarthy, Mark I., Morin-Papunen, Laure, Thorsteinsdottir, Unnur, Stefansson, Kari, Styrkarsdottir, Unnur, Perry, John R. B., Dunaif, Andrea, Laven, Joop, Franks, Steve, Lindgren, Cecilia M., Welt, Corrine K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300389/
https://www.ncbi.nlm.nih.gov/pubmed/30566500
http://dx.doi.org/10.1371/journal.pgen.1007813

Ejemplares similares

Ejemplares similares