Cargando…

Intraoperative visualization of the tumor microenvironment and quantification of extracellular vesicles by label-free nonlinear imaging

Characterization of the tumor microenvironment, including extracellular vesicles (EVs), is important for understanding cancer progression. EV studies have traditionally been performed on dissociated cells, lacking spatial information. Since the distribution of EVs in the tumor microenvironment is as...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sun, Yi, You, Sixian, Tu, Haohua, Spillman, Darold R., Chaney, Eric J., Marjanovic, Marina, Li, Joanne, Barkalifa, Ronit, Wang, Jianfeng, Higham, Anna M., Luckey, Natasha N., Cradock, Kimberly A., George Liu, Z., Boppart, Stephen A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300401/ https://www.ncbi.nlm.nih.gov/pubmed/30585292 http://dx.doi.org/10.1126/sciadv.aau5603

Ejemplares similares

Intraoperative Label-Free Multimodal Nonlinear Optical Imaging for Point-of-Procedure Cancer Diagnostics
por: Yang, Lingxiao, et al.
Publicado: (2021)

Label-free multimodal nonlinear optical imaging of needle biopsy cores for intraoperative cancer diagnosis
por: Yang, Lingxiao, et al.
Publicado: (2022)

Biomechanical sensing of in vivo magnetic nanoparticle hyperthermia-treated melanoma using magnetomotive optical coherence elastography
por: Huang, Pin-Chieh, et al.
Publicado: (2021)

Handheld optical coherence tomography for clinical assessment of dental plaque and gingiva
por: Won, Jungeun, et al.
Publicado: (2020)

Concurrence of extracellular vesicle enrichment and metabolic switch visualized label-free in the tumor microenvironment
por: Tu, Haohua, et al.
Publicado: (2017)

Non-invasive monitoring of pharmacodynamics during the skin wound healing process using multimodal optical microscopy
por: Rico-Jimenez, Jose, et al.
Publicado: (2020)

Assessing the Effect of Middle Ear Effusions on Wideband Acoustic Immittance Using Optical Coherence Tomography
por: Won, Jungeun, et al.
Publicado: (2019)

Video-rate multimodal multiphoton imaging and three-dimensional characterization of cellular dynamics in wounded skin
por: Li, Joanne, et al.
Publicado: (2020)

Assessing the severity of psoriasis through multivariate analysis of optical images from non-lesional skin
por: Žurauskas, Mantas, et al.
Publicado: (2020)

Real-time intraoperative diagnosis by deep neural network driven multiphoton virtual histology
por: You, Sixian, et al.
Publicado: (2019)

Raman Spectroscopic Analysis Reveals Abnormal Fatty Acid Composition in Tumor Micro- and Macroenvironments in Human Breast and Rat Mammary Cancer
por: You, Sixian, et al.
Publicado: (2016)

Label-free metabolic and structural profiling of dynamic biological samples using multimodal optical microscopy with sensorless adaptive optics
por: Iyer, Rishyashring R., et al.
Publicado: (2022)

Nonlinear Imaging Histopathology: A Pipeline to Correlate Gold-Standard Hematoxylin and Eosin Staining With Modern Nonlinear Microscopy
por: Tehrani, Kayvan Forouhesh, et al.
Publicado: (2023)

Real-time three-dimensional optical coherence tomography image-guided core-needle biopsy system
por: Kuo, Wei-Cheng, et al.
Publicado: (2012)

Simultaneous two-photon activation and imaging of neural activity based on spectral–temporal modulation of supercontinuum light
por: Liu, Yuan-Zhi, et al.
Publicado: (2020)

Dynamic Tracking Algorithm for Time-Varying Neuronal Network Connectivity using Wide-Field Optical Image Video Sequences
por: Renteria, Carlos, et al.
Publicado: (2020)

Weakly Supervised Identification and Localization of Drug Fingerprints Based on Label-Free Hyperspectral CARS Microscopy
por: Shi, Jindou, et al.
Publicado: (2023)

Clinical translation of handheld optical coherence tomography: practical considerations and recent advancements
por: Monroy, Guillermo L., et al.
Publicado: (2017)

Localization of unlabeled bepirovirsen antisense oligonucleotide in murine tissues using in situ hybridization and CARS imaging
por: Spencer-Dene, Bradley, et al.
Publicado: (2023)

Intravital imaging by simultaneous label-free autofluorescence-multiharmonic microscopy
por: You, Sixian, et al.
Publicado: (2018)

Nonlinear optical imaging by detection with optical parametric amplification (invited paper)
por: Sun, Yi, et al.
Publicado: (2023)

Intraoperative optical coherence tomography for assessing human lymph nodes for metastatic cancer
por: Nolan, Ryan M., et al.
Publicado: (2016)

Simultaneous label-free autofluorescence-multiharmonic microscopy and beyond
por: Boppart, Stephen A., et al.
Publicado: (2019)

Stain-free histopathology by programmable supercontinuum pulses
por: Tu, Haohua, et al.
Publicado: (2016)

Differential Uptake of Antisense Oligonucleotides in Mouse Hepatocytes and Macrophages Revealed by Simultaneous Two-Photon Excited Fluorescence and Coherent Raman Imaging
por: Mukherjee, Prabuddha, et al.
Publicado: (2022)

Non-invasive optical interferometry for the assessment of biofilm growth in the middle ear
por: Nguyen, Cac T., et al.
Publicado: (2010)

Multimodal Handheld Probe for Characterizing Otitis Media — Integrating Raman Spectroscopy and Optical Coherence Tomography
por: Monroy, Guillermo L., et al.
Publicado: (2022)

Automated classification platform for the identification of otitis media using optical coherence tomography
por: Monroy, Guillermo L., et al.
Publicado: (2019)

Nonlinear polarization dynamics in a weakly birefringent all-normal dispersion photonic crystal fiber: toward a practical coherent fiber supercontinuum laser
por: Tu, Haohua, et al.
Publicado: (2012)

Longitudinal optical coherence tomography to visualize the in vivo response of middle ear biofilms to antibiotic therapy
por: Won, Jungeun, et al.
Publicado: (2021)

Scalar generalized nonlinear Schrödinger equation-quantified continuum generation in an all-normal dispersion photonic crystal fiber for broadband coherent optical sources
por: Tu, Haohua, et al.
Publicado: (2010)

Handheld Briefcase Optical Coherence Tomography with Real-Time Machine Learning Classifier for Middle Ear Infections
por: Won, Jungeun, et al.
Publicado: (2021)

Label-free characterization of single extracellular vesicles using two-photon fluorescence lifetime imaging microscopy of NAD(P)H
por: Sorrells, Janet E., et al.
Publicado: (2021)

Computational Photon Counting Using Multithreshold Peak Detection for Fast Fluorescence Lifetime Imaging Microscopy
por: Sorrells, Janet E., et al.
Publicado: (2022)

Investigation of Nonlinear Pupil Dynamics by Recurrence Quantification Analysis
por: Mesin, L., et al.
Publicado: (2013)

Quantification of tumor fluorescence during intraoperative optical cancer imaging
por: Judy, Ryan P., et al.
Publicado: (2015)

Accurate Sphingolipid Quantification Reducing Fragmentation Bias by Nonlinear Models
por: Troppmair, Nina, et al.
Publicado: (2023)

Inferior displacement of the lower eyelid during intraoperative quantification in blepharoptosis surgery
por: Kakizaki, Hirohiko, et al.
Publicado: (2011)

Nonlinear dynamics in Divisia monetary aggregates: an application of recurrence quantification analysis
por: Andreadis, Ioannis, et al.
Publicado: (2023)

Innovative Visualization and Quantification of Extracellular Vesicles Interaction with and Incorporation in Target Cells in 3D Microenvironments
por: Ragni, Enrico, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_8i80jsda0ii2lv9uckdjojhbgt